MJF6101956

货号 规格 价格(¥)
MJF6101956S 50T
MJF6101956M 100T

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

直标流式抗体-Human CD191/CCR1 Antibody(F154),FITC

Datasheet

Background

Description

Chemokine receptor that plays a crucial role in regulating immune cell migration, inflammation, and immune responses . Contributes to the inflammatory response by recruiting immune cells, such as monocytes, macrophages, T-cells, and dendritic cells, to sites of inflammation for the clearance of pathogens and the resolution of tissue damage. When activated by its ligands including CCL3, CCL5-9, CCL13-16 and CCL23, triggers a signaling cascade within immune cells, leading to their migration towards the source of the chemokine . For example, mediates neutrophil migration after activation by CCL3 leading to the sequential release of TNF-alpha and leukotriene B4 (By similarity). Also mediates monocyte migration upon CXCL4 binding . Activation by CCL5 results in neuroinflammation through the ERK1/2 signaling pathway (By similarity). .

Uniprot

P32246

Alternative Names

C-C chemokine receptor type 1 (C-C CKR-1) (CC-CKR-1) (CCR-1) (CCR1) (HM145) (LD78 receptor) (Macrophage inflammatory protein 1-alpha receptor) (MIP-1alpha-R) (RANTES-R) (CD antigen CD191),CCR1 CMKBR1 CMKR1 SCYAR1,CMKR1, SCYAR1, Macrophage inflammatory protein 1-alpha receptor, CMKBR1, MIP-1alpha-R, HM145, CC-CKR-1, RANTES-R, LD78 receptor, CCR-1, C-C chemokine receptor type 1, CCR1, CD191, C-C CKR-1

Specificity

Application Image

Reactivity

Human

Application

FC

Recommended Dilution

FC 1:50-1:200

Mol weight

42kD

Conjugation

FITC

Source

Mouse

Immunogen

Clonality

Monoclonal

Clone No.

F154

Isotype

IgG1, kappa

Purification

Purity

Buffer

0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Concentration

0.5 mg/ml

Storage

Store at 4℃ for 12 months. Protect from light. Do not freeze.

Note

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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