Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates. .; (Microbial infection) Acts as an attachment receptor for Ebolavirus. .; (Microbial infection) Acts as an attachment receptor for Hepatitis C virus. .; (Microbial infection) Acts as an attachment receptor for HIV-1. .; (Microbial infection) Acts as an attachment receptor for Human coronavirus 229E. .; (Microbial infection) Acts as an attachment receptor for Human cytomegalovirus/HHV-5. .; (Microbial infection) Acts as an attachment receptor for Influenzavirus. .; (Microbial infection) Acts as an attachment receptor for SARS-CoV. .; (Microbial infection) Acts as an attachment receptor for West-nile virus. .; (Microbial infection) Acts as an attachment receptor for Japanese encephalitis virus. .; (Microbial infection) Acts as an attachment receptor for Marburg virus glycoprotein. .; (Microbial infection) Recognition of M.bovis by dendritic cells may occur partially via this molecule. .

Q9H2X3

C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (DC-SIGN-related protein) (DC-SIGNR) (Dendritic cell-specific ICAM-3-grabbing non-integrin 2) (DC-SIGN2) (Liver/lymph node-specific ICAM-3-grabbing non-integrin) (L-SIGN) (CD antigen CD299),CLEC4M CD209L CD209L1 CD299,DC-SIGNR, DC-SIGN2, CLEC4M, DC-SIGN-related protein, C-type lectin domain family 4 member M, CD299, L-SIGN, CD209L, Liver/lymph node-specific ICAM-3-grabbing non-integrin, CD209L1, Dendritic cell-specific ICAM-3-grabbing non-integrin 2, CD209 antigen-like protein 1

Human

FC

FC 1:50-1:200

46kD

PE

Mouse

Monoclonal

E413

IgG1, kappa

0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

0.5 mg/ml

Store at 4℃ for 12 months. Protect from light. Do not freeze.