HJJ463555

货号 规格 价格(¥)
HJJ463555S 50ul
HJJ463555M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-Human CD350/FZD10 Antibody(ON251)

Datasheet

Background

Description

Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues (Probable). .

Uniprot

q9ulw2

Alternative Names

Frizzled-10 (Fz-10) (hFz10) (FzE7) (CD antigen CD350),FZD10,FZD10, Fz-10, hFz10, Frizzled-10, CD350, FzE7

Specificity

Application Image

Reactivity

Human

Application

IHC,IP,FC,ELISA,RIA

Recommended Dilution

IHC 1:50-1:300
IP 1:50-1:200
FC 1:50-1:200
ELISA 1:5000-1:20000
RIA,The optimal dilutions should be determined by the end user.

Mol weight

66kD

Conjugation

Source

Human

Immunogen

Clonality

Monoclonal

Clone No.

ON251

Isotype

IgG1, kappa

Purification

Protein A/G purified from cell culture supernatant.

Purity

>95% as determined by SDS-PAGE.

Buffer

0.01M PBS, pH 7.4.

Concentration

1 mg/ml

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4℃ short term (1-2 weeks). Store at -20℃ 12 months.

Note

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北方及西南经销商负责:

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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