Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Dimeric G protein-coupled receptor which is activated by the excitatory neurotransmitter L-glutamate . Plays critical roles in modulating synaptic transmission and neuronal excitability. Upon activation by glutamate, inhibits presynaptic calcium channels, reducing further glutamate release and dampening excitatory signaling (By similarity). Mechanistically, ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization. .; (Microbial infection) Plays an important role in influenza virus internalization. .; (Microbial infection) Acts as a host entry factor for rabies virus that hijacks the endocytosis of GRM2 to enter cells. .; (Microbial infection) Acts as a host entry factor for SARS-CoV-2 that hijacks the endocytosis of GRM2 to enter cells. .
q14416
Metabotropic glutamate receptor 2 (mGluR2),GRM2 GPRC1B MGLUR2,Metabotropic glutamate receptor 2, GRM2, mGluR2, GPRC1B, MGLUR2
Human
ELISA
ELISA 1:5000-1:20000
96kD
Alpaca
Monoclonal
SA373
VHH-8His-Cys-tag
Purified by Nickel column.
>95% as determined by SDS-PAGE.
0.01M PBS, pH 7.4.
1 mg/ml
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4℃ short term (1-2 weeks). Store at -20℃ 12 months.
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