PJH742346

货号 规格 价格(¥)
PJH742346S 50ul
PJH742346M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-Human NRDE2 Antibody

Datasheet

Background

Description

Protein of the nuclear speckles that regulates RNA degradation and export from the nucleus through its interaction with MTREX an essential factor directing various RNAs to exosomal degradation . Changes the conformation of MTREX, precluding its association with the nuclear exosome and interaction with proteins required for its function in RNA exosomal degradation . Negatively regulates, for instance, the degradation of mRNAs and lncRNAs by inhibiting their MTREX-mediated recruitment to nuclear exosome . By preventing the degradation of RNAs in the nucleus, it promotes their export to the cytoplasm . U5 snRNP-associated RNA splicing factor which is required for efficient splicing of CEP131 pre-mRNA and plays an important role in centrosome maturation, integrity and function during mitosis . Suppresses intron retention in a subset of pre-mRNAs containing short, GC-rich introns with relatively weak 5'' and 3'' splice sites . Plays a role in DNA damage response . .

Uniprot

q9h7z3

Alternative Names

Nuclear exosome regulator NRDE2 (Protein NRDE2 homolog),NRDE2 C14orf102,Nuclear exosome regulator NRDE2, Protein NRDE2 homolog, C14orf102, NRDE2

Specificity

Application Image

Reactivity

Human

Application

WB,IHC,ELISA

Recommended Dilution

WB 1:500-1:2000
IHC 1:50-1:300
ELISA 1:5000-1:20000

Mol weight

133kD

Conjugation

Source

Rabbit

Immunogen

Recombinant Human NRDE2 (Thr162-Thr266).

Clonality

Polyclonal

Clone No.

Isotype

IgG

Purification

Purified by antigen affinity column.

Purity

Buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Concentration

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4℃ short term (1-2 weeks). Store at -20℃ 12 months.

Note

艾比玛特医药科技(上海)有限公司
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应聘职位:hr@ab-mart.com

订购专线:4006-123-828

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技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

46c73bc4c7a4d51a3ce472aedb80205b_compress.jpg

      微信客服

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