MJH9106659

货号 规格 价格(¥)
MJH9106659S 50T
MJH9106659M 100T

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

直标流式抗体-Human P2RX4 Antibody(SA1113),PerCP

Datasheet

Background

Description

ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and calcium . CTP, but not GTP or UTP, functions as a weak affinity agonist for P2RX4 (By similarity). Activated by extracellularly released ATP, it plays multiple role in immunity and central nervous system physiology . Plays a key role in initial steps of T-cell activation and Ca(2+) microdomain formation (By similarity). Also participates in basal T-cell activity without TCR/CD3 stimulation (By similarity). Promotes the differentiation and activation of Th17 cells via expression of retinoic acid-related orphan receptor C/RORC . Upon activation, drives microglia motility via the PI3K/Akt pathway (By similarity). Could also function as an ATP-gated cation channel of lysosomal membranes (By similarity). .

Uniprot

Q99571

Alternative Names

P2X purinoceptor 4 (P2X4) (ATP receptor) (Purinergic receptor),P2RX4,Purinergic receptor, P2RX4, P2X4, P2X purinoceptor 4, ATP receptor

Specificity

Application Image

Reactivity

Human

Application

FC,ELISA

Recommended Dilution

FC 1:50-1:200
ELISA 1:5000-1:20000

Mol weight

44kD

Conjugation

PerCP

Source

Mouse

Immunogen

Clonality

Monoclonal

Clone No.

SA1113

Isotype

IgG2a, kappa

Purification

Purity

Buffer

0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Concentration

0.5 mg/ml

Storage

Store at 4℃ for 12 months. Protect from light. Do not freeze.

Note

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邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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