Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
ADP-ribosyltransferase that mediates mono-ADP-ribosylation of glutamate residues on target proteins . In contrast to PARP1 and PARP2, it is not able to mediate poly-ADP-ribosylation . Has been shown to catalyze the mono-ADP-ribosylation of STAT1 at ''Glu-657'' and ''Glu-705'', thus decreasing STAT1 phosphorylation which negatively regulates pro-inflammatory cytokine production in macrophages in response to IFNG stimulation . However, the role of ADP-ribosylation in the prevention of STAT1 phosphorylation has been called into question and it has been suggested that the inhibition of phosphorylation may be the result of sumoylation of STAT1 ''Lys-703'' . Mono-ADP-ribosylates STAT6; enhancing STAT6-dependent transcription . In macrophages, positively regulates MRC1 expression in response to IL4 stimulation by promoting STAT6 phosphorylation . Mono-ADP-ribosylates PARP9 . .
q460n5
Protein mono-ADP-ribosyltransferase PARP14 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2) (Poly [ADP-ribose] polymerase 14) (PARP-14),PARP14 BAL2 KIAA1268,BAL2, B aggressive lymphoma protein 2, PARP14, Poly [ADP-ribose] polymerase 14, Protein mono-ADP-ribosyltransferase PARP14, PARP-14, ADP-ribosyltransferase diphtheria toxin-like 8, KIAA1268, ARTD8
Human
IF,ICC,IP,ELISA
IF 1:100-1:500ICC 1:100-1:400IP 1:50-1:200ELISA 1:5000-1:20000
203kD
Mouse
Monoclonal
SA459
IgG1
Protein A/G purified from cell culture supernatant.
>95% as determined by SDS-PAGE.
0.01M PBS, pH 7.4.
1 mg/ml
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4℃ short term (1-2 weeks). Store at -20℃ 12 months.
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订购专线:4006-123-828
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华南经销商负责(广东,广西,福建,海南):
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