Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Pore-forming protein that plays a key role in granzyme-mediated programmed cell death, and in defense against virus-infected or neoplastic cells . Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease . Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores . Promotes cytolysis and apoptosis of target cells by mediating the passage and uptake of cytotoxic granzymes . Facilitates the delivery of cationic cargo protein, while anionic or neural proteins are not delivered efficiently . Perforin pores allow the release of mature caspase-7 (CASP7) into the extracellular milieu (By similarity). .
P14222
Perforin-1 (P1) (Cytolysin) (Lymphocyte pore-forming protein) (PFP),PRF1 PFP,Cytolysin, Perforin-1, Lymphocyte pore-forming protein, PFP, PRF1, P1
Human
FC
FC 1:50-1:200
62kD
FITC
Mouse
Monoclonal
SA350
IgG1, kappa
0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.
0.5 mg/ml
Store at 4℃ for 12 months. Protect from light. Do not freeze.
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订购专线:4006-123-828
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