Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Repair polymerase that plays a key role in base-excision repair . During this process, the damaged base is excised by specific DNA glycosylases, the DNA backbone is nicked at the abasic site by an apurinic/apyrimidic (AP) endonuclease, and POLB removes 5''-deoxyribose-phosphate from the preincised AP site acting as a 5''-deoxyribose-phosphate lyase (5''-dRP lyase); through its DNA polymerase activity, it adds one nucleotide to the 3'' end of the arising single-nucleotide gap . Conducts ''gap-filling'' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. It is also able to cleave sugar-phosphate bonds 3'' to an intact AP site, acting as an AP lyase . .
p06746
DNA polymerase beta (EC 2.7.7.7) (5''-deoxyribose-phosphate lyase) (5''-dRP lyase) (EC 4.2.99.-) (AP lyase) (EC 4.2.99.18),POLB,DNA polymerase beta, POLB
Human
WB,IHC,ELISA
WB 1:500-1:2000IHC 1:50-1:300ELISA 1:5000-1:20000
39kD
Rabbit
Recombinant Human POLB (Asn12-Glu335).
Polyclonal
IgG
Purified by antigen affinity column.
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4℃ short term (1-2 weeks). Store at -20℃ 12 months.
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