Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
DNA helicase that plays an important role in DNA replication, transcription and repair . Probably unwinds DNA in a 3''-5'' direction (Probable) . Binds to the RNA polymerase II subunit POLR2A during transcription elongation and suppresses transcription-associated genomic instability . Also associates with POLR1A and enforces the stability of ribosomal DNA arrays . Plays an important role in mitotic chromosome separation after cross-over events and cell cycle progress . Mechanistically, removes RAD51 filaments protecting stalled replication forks at common fragile sites and stimulates MUS81-EME1 endonuclease leading to mitotic DNA synthesis . Required for efficient DNA repair, including repair of inter-strand cross-links . Stimulates DNA decatenation mediated by TOP2A. Prevents sister chromatid exchange and homologous recombination. A core helicase fragment (residues 11-609) binds preferentially to splayed duplex, looped and ssDNA . .
o94762
ATP-dependent DNA helicase Q5 (EC 5.6.2.4) (DNA 3''-5'' helicase RecQ5) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5),RECQL5 RECQ5,RECQ5, RecQ protein-like 5, RecQ5, DNA helicase, RecQ-like type 5, ATP-dependent DNA helicase Q5, RECQL5
Human
ELISA
ELISA 1:5000-1:20000
109kD
Alpaca
Monoclonal
SA381
VHH-8His-Cys-tag
Purified by Nickel column.
>95% as determined by SDS-PAGE.
0.01M PBS, pH 7.4.
1 mg/ml
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4℃ short term (1-2 weeks). Store at -20℃ 12 months.
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