Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Histone methyltransferase that specifically monomethylates ''Lys-4'' of histone H3 . H3 ''Lys-4'' methylation represents a specific tag for epigenetic transcriptional activation . Plays a central role in the transcriptional activation of genes such as collagenase or insulin . Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription . Also has methyltransferase activity toward non-histone proteins such as CGAS, p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins . Monomethylates ''Lys-189'' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II . Monomethylates ''Lys-372'' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation . Monomethylates ''Lys-491'' of CGAS, promoting interaction between SGF29 and CGAS (By similarity). .
q8wts6
Histone-lysine N-methyltransferase SETD7 (EC 2.1.1.364) (Histone H3-K4 methyltransferase SETD7) (H3-K4-HMTase SETD7) (Lysine N-methyltransferase 7) (SET domain-containing protein 7) (SET7/9),SETD7 KIAA1717 KMT7 SET7 SET9,Lysine N-methyltransferase 7, SET9, SET7/9, Histone H3-K4 methyltransferase SETD7, SET7, SET domain-containing protein 7, SETD7, H3-K4-HMTase SETD7, KIAA1717, Histone-lysine N-methyltransferase SETD7, KMT7
Human
WB,IHC,ELISA
WB 1:500-1:2000IHC 1:50-1:300ELISA 1:5000-1:20000
41kD
Rabbit
Recombinant Human SETD7 (Met1-Lys366).
Polyclonal
IgG
Purified by antigen affinity column.
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4℃ short term (1-2 weeks). Store at -20℃ 12 months.
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应聘职位:hr@ab-mart.com
订购专线:4006-123-828
销售电话:13916964679(微信同号)
技术支持:15618194176(微信同号)
华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
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