Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically trimethylates histone H3 ''Lys-4'' (H3K4me3) in vivo. The activity requires interaction with HSP90alpha. Shows even higher methyltransferase activity on p53/TP53. Monomethylates ''Lys-370'' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at ''Lys-860''. .
q9nrg4
N-lysine methyltransferase SMYD2 (EC 2.1.1.-) (HSKM-B) (Histone methyltransferase SMYD2) (EC 2.1.1.354) (Lysine N-methyltransferase 3C) (SET and MYND domain-containing protein 2),SMYD2 KMT3C,HSKM-B, N-lysine methyltransferase SMYD2, Histone methyltransferase SMYD2, SMYD2, SET and MYND domain-containing protein 2, Lysine N-methyltransferase 3C, KMT3C
Human
IF,ICC,IP,ELISA
IF 1:100-1:500ICC 1:100-1:400IP 1:50-1:200ELISA 1:5000-1:20000
50kD
Mouse
Monoclonal
SA475
IgG2a
Protein A/G purified from cell culture supernatant.
>95% as determined by SDS-PAGE.
0.01M PBS, pH 7.4.
1 mg/ml
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4℃ short term (1-2 weeks). Store at -20℃ 12 months.
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