Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Chromatin reader that recognizes dual histone modifications such as histone H3.1 dimethylated at ''Lys-36'' and histone H4 acetylated at ''Lys-16'' (H3.1K36me2-H4K16ac) and histone H3 methylated at ''Lys-4'' and histone H4 acetylated at ''Lys-14'' (H3K4me1-H3K14ac) . May act as a transcriptional corepressor for KDM5D by recognizing the dual histone signature H3K4me1-H3K14ac . May also act as a transcriptional corepressor for KDM5C and EZH2 . Recognizes acetylated histone H4 and recruits the NuRD chromatin remodeling complex to damaged chromatin for transcriptional repression and double-strand break repair by homologous recombination . Also activates transcription elongation by RNA polymerase II through recruiting the P-TEFb complex to target promoters . Localizes to H3.1K36me2-H4K16ac marks at all-trans-retinoic acid (ATRA)-responsive genes and positively regulates their expression . Promotes neuronal differentiation by associating with regulatory regions within the MAPT gene, to enhance transcription of a protein-coding MAPT isoform and suppress the non-coding MAPT213 isoform . Suppresses breast cancer, and prostate cancer cell invasion and metastasis . .
q9ulu4
MYND-type zinc finger-containing chromatin reader ZMYND8 (Cutaneous T-cell lymphoma-associated antigen se14-3) (CTCL-associated antigen se14-3) (Protein kinase C-binding protein 1) (Rack7) (Transcription coregulator ZMYND8) (Zinc finger MYND domain-containing protein 8),ZMYND8 KIAA1125 PRKCBP1 RACK7,Protein kinase C-binding protein 1, PRKCBP1, RACK7, ZMYND8, CTCL-associated antigen se14-3, Cutaneous T-cell lymphoma-associated antigen se14-3, Rack7, KIAA1125, Zinc finger MYND domain-containing protein 8
Human
WB,IHC,ELISA
WB 1:500-1:2000IHC 1:50-1:300ELISA 1:5000-1:20000
132kD
Rabbit
Recombinant Human ZMYND8 (His111-Thr388).
Polyclonal
IgG
Purified by antigen affinity column.
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4℃ short term (1-2 weeks). Store at -20℃ 12 months.
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邮箱:market@ab-mart.com
应聘职位:hr@ab-mart.com
订购专线:4006-123-828
销售电话:13916964679(微信同号)
技术支持:15618194176(微信同号)
华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:
陆经理:手机13122837132(微信同号)
北方及西南经销商负责:
张经理:手机13122150513(微信同号)

微信客服
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