HJL1106046

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HJL1106046S 50ug
HJL1106046M 100ug
HJL1106046L 1000ug

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

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   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-Listeria monocytogenes serovar 1/2a InlB/Internalin B Antibody(SA609)

Datasheet

Background

Description

Mediates the entry of L.monocytogenes into normally non-phagocytic mammalian host cells . Its host receptor is hepatocyte growth factor receptor (HGF receptor, a tyrosine kinase, MET) which is tyrosine-phosphorylated in response to InlB. Downstream targets MAPK1/MAPK3 (Erk1/2) and AKT are phosphorylated in response to InlB, which also causes cell colony scattering . Complement component 1 Q subcomponent-binding protein (gC1q-R, C1QBP) has been suggested to also act an InlB receptor, but this is less certain. Stimulation of Tyr-phosphorylation of MET by InlB is potentiated by the InlB GW domains and glycosaminoglycans such as heparin (By similarity). .

Uniprot

p0dqd2, p0dqd3

Alternative Names

Internalin B (InlB) (Invasion protein InlB),inlB lmo0434,Internalin B, InlB, Invasion protein InlB, inlB, lmo0434

Specificity

Application Image

Reactivity

Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e), Listeria monocytogenes serotype 1/2a (strain EGD / Mackaness)

Application

ELISA,Neutralization,SPR

Recommended Dilution

ELISA 1:5000-1:20000
Neutralization,SPR,The optimal dilutions should be determined by the end user.

Mol weight

72kD

Conjugation

Source

Human

Immunogen

Clonality

Monoclonal

Clone No.

SA609

Isotype

VHH-huFc

Purification

Protein A/G purified from cell culture supernatant.

Purity

>95% as determined by SDS-PAGE.

Buffer

0.01M PBS, pH 7.4.

Concentration

1 mg/ml

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4℃ short term (1-2 weeks). Store at -20℃ 12 months.

Note

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邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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