13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Receptor for the invariable Fc fragment of immunoglobulin gamma (IgG) . Binds with intermediate affinity to both IgG2a and IgG2b . Can bind to IgG2a and IgG2b monomers . Does not display binding to IgG1 or IgG3 . Recognizes neutralizing virus-specific IgGs displayed on the cell surface of infected cells and triggers antibody-dependent cellular cytotoxicity (ADCC). Confers protection to lethal influenza virus infection . On splenic dendritic cells, uptakes antigen immune complexes and efficiently divert them into MHC class I and II antigen presentation pathways to provide for superior priming of CD4-positive and CD8-positive T cell immune responses . Mediates neutrophil activation by IgG complexes redundantly with FCGR2A . Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a . Also acts as a receptor for the Fc region of immunoglobulin epsilon (IgE) . Binds with low affinity to both the a and b allotypes of IgE . Has also been shown to bind to IgE allotype a only but not to allotype b . Binds aggregated IgE but not the monomeric form and bound monomeric IgG is readily displaced by IgE complexes . Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of pro-inflammatory cytokines and the late phase of cutaneous allergic reactions . Mediates enhanced ADCC in response to afucosylated IgGs . .
a0a0b4j1g0
Low affinity immunoglobulin gamma Fc region receptor III-A (IgG Fc receptor III-A) (CD16-2) (FcgammaRIV) (CD antigen CD16a),Fcgr4 Fcgr3a,Low affinity immunoglobulin gamma Fc region receptor III-A (IgG Fc receptor III-A) (CD16-2) (FcgammaRIV) (CD antigen CD16a)
Mouse
WB,IHC,ELISA
WB 1:500-1:2000IHC 1:50-1:300ELISA 1:5000-1:20000
29kD
Rabbit
Recombinant Mouse CD16a/FCGR3A/Fcgr4 (Lys24-Gly190).
Polyclonal
IgG
Purified by antigen affinity column.
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4℃ short term (1-2 weeks). Store at -20℃ 12 months.
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微信客服
邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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