Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Receptor involved in axon guidance during development. Acts as a multifunctional regulator of pathfinding that simultaneously mediates NELL2 repulsion, inhibits SLIT repulsion, and facilitates Netrin-1/NTN1 attraction . In spinal cord development plays a role in guiding commissural axons probably by preventing premature sensitivity to Slit proteins thus inhibiting Slit signaling through ROBO1/ROBO2 . Binding OF NELL2 to the receptor ROBO3 promotes oligomerization of ROBO3, resulting in the repulsion of commissural axons in the midline . ROBO3 also indirectly boosts axon attraction to NTN1 without interacting with NTN1 itself . .; [Isoform 1]: Mediates NELL2 premature repulsion of commissural axons during midline crossing. .; [Isoform 2]: After midline crossing by the commissural axons, may, in concert with ROBO1 and ROBO2, prevent midline recrossing. Does not mediate NELL2 signaling. .
q9z2i4
Roundabout homolog 3 (Retinoblastoma-inhibiting gene 1 protein) (Rig-1) (Roundabout guidance receptor 3),Robo3 Rbig1,Roundabout-like protein 3, ROBO3, Roundabout homolog 3
Mouse
WB,IHC,ELISA
WB 1:500-1:2000IHC 1:50-1:300ELISA 1:5000-1:20000
150kD
Rabbit
Recombinant Mouse ROBO3 (Gly173-Val345).
Polyclonal
IgG
Purified by antigen affinity column.
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4℃ short term (1-2 weeks). Store at -20℃ 12 months.
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