[Capsid polyprotein VP90]: The capsid polyprotein VP90 self-assembles and undergoes a proteolytic cleavage by host caspases to yield the immature VP70 virion. .; [Capsid polyprotein VP70]: The immature virion is composed of 180 VP70 subunits with 90 dimeric spikes and displays a T=3 icosahedral symmetry . During maturation, VP70 undergoes a loss of 60 peripentonal spikes, which likely plays an important role in viral infectivity . .; [Core protein VP34]: Self-assembles to form an icosahedral capsid with a T=3 symmetry, about 43 nm in diameter . This forms contains only 30 spikes located on the icosahedral 2-fold axes . .; [Spike protein VP27]: VP25 and VP27 Forms the spikes at the surface of the virion . This forms contains only 30 spikes located on the icosahedral 2-fold axes. Plays a role in the attachment to target host cell (Probable). This attachment induces virion internalization through clathrin-dependent endocytosis . .; [Spike protein VP25]: VP25 and VP27 Forms the spikes at the surface of the virion . This forms contains only 30 spikes located on the icosahedral 2-fold axes . Plays a role in the attachment to target host cell . This attachment induces virion internalization through clathrin-dependent endocytosis . .

q9ifx1

Capsid polyprotein VP90 [Cleaved into: Capsid polyprotein VP70; Core protein VP34; Spike protein VP27; Spike protein VP25],ORF2

Human astrovirus-8

ELISA,Neutralization

ELISA 1:5000-1:20000
Neutralization,The optimal dilutions should be determined by the end user.

86kD

Human

Monoclonal

E284

IgG1

Protein A/G purified from cell culture supernatant.

>95% as determined by SDS-PAGE.

0.01M PBS, pH 7.4.

1 mg/ml

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4℃ short term (1-2 weeks). Store at -20℃ 12 months.

For research use only. Not suitable for clinical or therapeutic use.