Lectin that plays a role in innate immunity, apoptosis and embryogenesis . Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope . Primarily recognizes the terminal disaccharide of the glycan . Also recognizes a subset of fucosylated glycans and lipopolysaccharides . Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1 . Also plays a role in apoptosis through its ability to bind in a calcium-independent manner the DNA present at the surface of apoptotic cells and to activate the complement in response to this binding (Probable). Finally, plays a role in development, probably serving as a guidance cue during the migration of neural crest cells and other cell types during embryogenesis .

Q9BWP8

78989

Collectin-11, Collectin kidney protein 1, CL-K1, COLEC11

Human,Mouse,Rat

WB,IHC,FC

WB 1:1000
IHC 1:100-500
FC 1:10-50

29 kD

Rabbit

Polyclonal

Rabbit IgG

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

PBS (pH7.4) with 0.09% (W/V) sodium azide.

Store at -20°C. Stable for 12 months from date of receipt.Do not aliquot the antibody.Avoid freeze / thaw cycle.