RY322074

货号 规格 价格(¥)
RY322074S 50ul
RY322074M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-Mouse Cbx7 Antibody

Datasheet

Background

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development . PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A ''Lys-119'', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at ''Lys-9'' (H3K9me3) (By similarity). Binds to histone H3 trimethylated at ''Lys-9'' (H3K9me3) or at ''Lys-27'' (H3K27me3) . Trimethylation at ''Lys-27'' (H3K27me3) is important for chromatin recruitment . May possibly also bind trimethylated lysine residues in other proteins (in vitro) . Binds non-coding, single-stranded RNA and double-stranded RNA . Plays a role in the timely repression of differentiation-specific genes in pluripotent embryonic stem cells to maintain the undifferentiated state . Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity .

Uniprot

Q8VDS3

Gene ID

52609

Alternative Name

Chromobox protein homolog 7, Cbx7, D15Ertd417e

Reactivity

Human,Mouse,Rat

Application Image

Application

WB

Recommended Dilution

WB 1:1000

Mol Weight

19 kD

Source

Rabbit

Clonality

polyclonal

Isotype

Rabbit IgG

Purification

This antibody is purified by peptide affinity purification.

Buffer

PBS (pH7.4) with 0.09% (W/V) sodium azide.

Storage

Store at -20°C. Stable for 12 months from date of receipt.Do not aliquot the antibody.Avoid freeze / thaw cycle.

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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