Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012],

Type-1 angiotensin II receptor,AGTR1;AGTR1A;AGTR1B;AT2R1;AT2R1B;Type-1 angiotensin II receptor;AT1AR;AT1BR;Angiotensin II type-1 receptor;AT1;AGTR1A;AGTR1B;AT2R1;AT2R1B,AGTR1

P30556,P25095

Human,Mouse,Rat

WB,IHC,IF,ICC,ELISA

WB 1:500-1:2000
IHC 1:50-1:200
IF 1:200-1:1000
ICC 1:200-1:1000
ELISA 1:5000-1:20000

36kDa

Cell membrane ; Multi-pass membrane protein .

Rabbit

Monoclonal

IgG,Kappa

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

-20°C/1 year(Do not lower than -25°C)