TP71332

货号 规格 价格(¥)
TP71332S 50μl
TP71332M 100μl

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

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   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-AZI1 Antibody

Datasheet

Background

Component of centriolar satellites contributing to the building of a complex and dynamic network required to regulate cilia/flagellum formation . In proliferating cells, MIB1-mediated ubiquitination induces its sequestration within centriolar satellites, precluding untimely cilia formation initiation . In contrast, during normal and ultraviolet or heat shock cellular stress-induced ciliogenesis, its non-ubiquitinated form is rapidly displaced from centriolar satellites and recruited to centrosome/basal bodies in a microtubule- and p38 MAPK-dependent manner . Acts also as a negative regulator of BBSome ciliary trafficking . Plays a role in sperm flagellar formation; may be involved in the regulation of intraflagellar transport (IFT) and/or intramanchette (IMT) trafficking, which are important for axoneme extension and/or cargo delivery to the nascent sperm tail (By similarity). Required for optimal cell proliferation and cell cycle progression; may play a role in the regulation of genome stability in non-ciliogenic cells . Involved in centriole duplication (By similarity). Required for CEP152, WDR62 and CEP63 centrosomal localization and promotes the centrosomal localization of CDK2 . Essential for maintaining proper centriolar satellite integrity . .

Alternative Name

Centrosomal protein of 131 kDa (5-azacytidine-induced protein 1) (Pre-acrosome localization protein 1) CEP131 AZI1 KIAA1118

Reactivity

Human

Predicted Reactivity

Application

WB,IHC

Application Image

Recommended Dilution

WB 1:500-1:1000
IHC 1:50-1:200

Mol Weight

130 KD

Gene Symbol

CEP131 AZI1 KIAA1118

Uniprot

q9upn4

Uniprot link

Immunogen

Immunogen Range

Source

Rabbit

Clonality

Polyclonal

Isotype

Rabbit IgG

Specificity

Subcellular location

Research Area

Cell cycle

Positive control

Conjugation

Modification

Purification

Formulation

Concentration

Buffer

PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

产品介绍

Clone

Target

波长

Storage

Store at -20 °C. Stable for 12 months from date of receipt.

注意事项

Companion Products

Important

Comments

RRID

客户评价

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北方及西南经销商负责:

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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