Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Receptor for endocannabinoid N-arachidonyl glycine (NAGly) . However, conflicting results about the role of NAGly as an agonist are reported . Can also be activated by plant-derived and synthetic cannabinoid agonists . The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase . May contribute to regulation of the immune system. Is required for normal homeostasis of CD8+ subsets of intraepithelial lymphocytes (IELs) (CD8alphaalpha and CD8alphabeta IELs)in small intstine by supporting preferential migration of CD8alphaalpha T-cells to intraepithelial compartment over lamina propria compartment, and by mediating their reconstitution into small intestine after bone marrow transplant (By similarity). Plays a role in hypotensive responses, mediating reduction in intraocular and blood pressure (By similarity). Mediates NAGly-induced process of reorganization of actin filaments and induction of acrosomal exocytosis . .
N-arachidonyl glycine receptor (NAGly receptor) (G-protein coupled receptor 18) GPR18 GPCRW
Human
WB,IF,ICC
WB 1:500-1:1000IF 1:100-1:500ICC 1:100-1:500
35 KD
GPR18 GPCRW
q14330
Rabbit
Polyclonal
Rabbit IgG
Transmembrane
G protein-coupled receptor signaling pathway
PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Store at -20 °C. Stable for 12 months from date of receipt.
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