13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
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Component of the small ribosomal subunit . The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell . Has endonuclease activity and plays a role in repair of damaged DNA . Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA . Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS) . Has also been shown to bind with similar affinity to intact and damaged DNA . Stimulates the N-glycosylase activity of the base excision protein OGG1 . Enhances the uracil excision activity of UNG1 . Also stimulates the cleavage of the phosphodiester backbone by APEX1 . When located in the mitochondrion, reduces cellular ROS levels and mitochondrial DNA damage . Has also been shown to negatively regulate DNA repair in cells exposed to hydrogen peroxide . Plays a role in regulating transcription as part of the NF-kappa-B p65-p50 complex where it binds to the RELA/p65 subunit, enhances binding of the complex to DNA and promotes transcription of target genes . Represses its own translation by binding to its cognate mRNA . Binds to and protects TP53/p53 from MDM2-mediated ubiquitination . Involved in spindle formation and chromosome movement during mitosis by regulating microtubule polymerization . Involved in induction of apoptosis through its role in activation of CASP8 . Induces neuronal apoptosis by interacting with the E2F1 transcription factor and acting synergistically with it to up-regulate pro-apoptotic proteins BCL2L11/BIM and HRK/Dp5 . Interacts with TRADD following exposure to UV radiation and induces apoptosis by caspase-dependent JNK activation . .
Small ribosomal subunit protein uS3 (40S ribosomal protein S3) (EC 4.2.99.18) RPS3 OK/SW-cl.26
Human,Mouse,Rat
WB,IHC
WB 1:500-1:1000IHC 1:50-1:200
30 KD
RPS3 OK/SW-cl.26
p23396
Rabbit
Polyclonal
Rabbit IgG
Apoptosis #Cell division #Chromosome partition #DNA damage #DNA excision #negative regulation of translation
PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Store at -20 °C. Stable for 12 months from date of receipt.
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邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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