Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Glutamate is the main excitatory neurotransmitter in the brain. For many years it had been considered to act only on the ligand-gated receptor channels-termed NMDA, AMPA and kainite receptors that are involved in the fast excitatory synaptic transmission. Recently, glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins. These receptors are called metabotropic glutamate receptors. In expression systems, Group-I receptors stimulate phospholipase C as revealed by an increase in phosphoinositide turnover and calcium release from internal stores. Group-II and -III receptors are coupled to the inhibition of adenylyl cyclase. The Group-I receptors include mGluR1a and mGluR5. The Group-II receptors in include mGluR2 and mGluR3.
Metabotropic glutamate receptor 1 (mGluR1)GRM1 GPRC1A MGLUR1
Human
WB,IF,ICC
WB 1:1000-1:2000IF 1:100-1:1000ICC 1:100-1:400
132 kDa
GRM1 GPRC1A MGLUR1
q13255
Mouse
Monoclonal
Mouse IgG
GRM1 Antibody detects endogenous levels of total GRM1.
Transmembrane
chemical synaptic transmission #G protein-coupled receptor signaling pathway
PBS, pH 7.4, 40% glycerol, and 0.01% sodium azide.
Store at -20 °C. Stable for 12 months from date of receipt.Store at -20°C long term.
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