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Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
ABCB11 is involved in the ATP-dependent secretion of bile salts into the canaliculus of hepatocytes. It is expressed predominatly, if not exclusively, in the liver, where it is further localized to the canilicular microvilli and to subcanilicular vesicles fo the hepatocytes. Structurally, ABCB11 is a multifunctional polypeptide with two homologus halves, each containing a hydrophobic membrane-anchoring domain and an ATP binding cassette (ABC) domain. Defects in ABCB11 are the cause of progressive familial intrahepatic cholestasis 2 (PFIC2). PFIC2 is an inherited liver disease of childhood which is characterized by cholestasis and normal serum gamma-glutamyltransferase activity. Defects in ABCB11 are also found in cases of chronic intrahepatic cholestasis without obvious familial history of chronic liver disease.
Bile salt export pump (EC 7.6.2.-) (ATP-binding cassette sub-family B member 11)ABCB11 BSEP
Human, Mouse, Rat
WB,IHC,IF,ICC
WB 1:1000-1:2000IHC 1:100-1:1000IF 1:100-1:1000ICC 1:100-1:400
146 kDa
ABCB11 BSEP
o95342
Mouse
Monoclonal
Mouse IgG
Antibody detects endogenous levels of total ABCB11.
Transmembrane
Fatty acid metabolism
PBS, pH 7.4, 40% glycerol, and 0.01% sodium azide.
Store at -20 °C. Stable for 12 months from date of receipt.Store at -20°C long term.
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应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
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程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
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