Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Apoptosis-inducing protein that can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. Plays an important role in the calprotectin (S100A8/A9)-induced cell death pathway.
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 BNIP3 NIP3
Human
IHC,IF,ICC,ELISA
IHC 1:20-1:200IF 1:50-1:200ICC 1:100-1:400ELISA 1:5000-1:20000
27.832 kDa ;
BNIP3 NIP3
q12983
Recombinant Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 protein (1-164AA)
Rabbit
Polyclonal
IgG
Transmembrane
Cancer; Cardiovascular; Cell biology; Metabolism; Microbiology
>95%, Antigen Affinity Purified
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Store at -20°C. Do not aliquot the antibody
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