Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3\\\\\\'-UTR of many proto-oncogenes and cytokine mRNAs. Also binds to double- and single-stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single-stranded non-monotonous 5\\\\\\'-UUAG-3\\\\\\' sequence and also weaker to the single-stranded 5\\\\\\'-TTAGGG-3\\\\\\' telomeric DNA repeat. Binds RNA oligonucleotides with 5\\\\\\'-UUAGGG-3\\\\\\' repeats more tightly than the telomeric single-stranded DNA 5\\\\\\'-TTAGGG-3\\\\\\' repeats. Binding of RRM1 to DNA inhibits the formation of DNA quadruplex structure which may play a role in telomere elongation. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. May play a role in the regulation of the rhythmic expression of circadian clock core genes. Directly binds to the 3\\\\\\'UTR of CRY1 mRNA and induces CRY1 rhythmic translation. May also be involved in the regulation of PER2 translation.
Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1) HNRNPD AUF1 HNRPD
Human
WB,IHC,ELISA
WB 1:500-1:1000IHC 1:20-1:200ELISA 1:5000-1:20000
38.434 kDa ;
HNRNPD AUF1 HNRPD
q14103
Recombinant Human Heterogeneous nuclear ribonucleoprotein D0 protein (1-306AA)
Rabbit
Polyclonal
IgG
Epigenetics and Nuclear Signaling
>95%, Antigen Affinity Purified
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Store at -20°C. Do not aliquot the antibody
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订购专线:4006-123-828
销售电话:13916964679(微信同号)
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华南经销商负责(广东,广西,福建,海南):
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徐经理:手机15618191473(微信同号)
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