Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP (PubMed:9624146, PubMed:18757755, PubMed:21483814). Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart (PubMed:25799991). Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein (Probable). In brain, involved in cognitive function, such as learning and long-term memory (By similarity).
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35) PDE9A
Human
WB,IHC,IF,ICC,ELISA
WB 1:500-1:5000IHC 1:500-1:1000IF 1:200-1:500ICC 1:100-1:400ELISA 1:5000-1:20000
68.493 kDa ;
PDE9A
o76083
Recombinant Human High affinity cGMP-specific 3\\\\\\',5\\\\\\'-cyclic phosphodiesterase 9A protein (426-533AA)
Rabbit
Polyclonal
IgG
Signal transduction
>95%, Protein G purified
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Store at -20°C. Do not aliquot the antibody
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