PHR0642

货号 规格 价格(¥)
PHR0642S 50μl
PHR0642M 100μl

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

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   免疫荧光

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   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-PIWIL1 Antibody

Datasheet

Background

Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Directly binds methylated piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Besides their function in transposable elements repression, piRNAs are probably involved in other processes during meiosis such as translation regulation. Probable component of some RISC complex, which mediates RNA cleavage and translational silencing. Also plays a role in the formation of chromatoid bodies and is required for some miRNAs stability (By similarity). Isoform 3 may be a negative developmental regulator (PubMed:12037681, PubMed:16287078).

Alternative Name

Piwi-like protein 1 (EC 3.1.26.-) PIWIL1 HIWI

Reactivity

Human

Predicted Reactivity

Application

IHC,ELISA

Application Image

Recommended Dilution

IHC 1:20-1:200
ELISA 1:5000-1:20000

Mol Weight

98.603 kDa ;

Gene Symbol

PIWIL1 HIWI

Uniprot

q96j94

Uniprot link

Immunogen

Recombinant Human Piwi-like protein 1 protein (390-690AA)

Immunogen Range

Source

Rabbit

Clonality

Polyclonal

Isotype

IgG

Specificity

Subcellular location

Research Area

Epigenetics and Nuclear Signaling

Positive control

Conjugation

Modification

Purification

>95%, Antigen Affinity Purified

Formulation

Concentration

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

产品介绍

Clone

Target

波长

Storage

Store at -20°C. Do not aliquot the antibody

注意事项

Companion Products

Important

Comments

RRID

客户评价

艾比玛特医药科技(上海)有限公司
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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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