PH3045

货号 规格 价格(¥)
PH3045S 50μl
PH3045M 100μl

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

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经典一抗-PARG Antibody

Datasheet

Background

Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase (PubMed:23102699). PARG acts both as an endo- and exoglycosidase, releasing PAR of different length as well as ADP-ribose monomers (PubMed:23102699). Required for retinoid acid-dependent gene transactivation, probably by dePARsylating histone demethylase KDM4D, allowing chromatin derepression at RAR-dependent gene promoters (PubMed:23102699). Involved in the synthesis of ATP in the nucleus, together with PARP1, NMNAT1 and NUDT5 (PubMed:27257257). Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming (PubMed:27257257).

Alternative Name

Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143) PARG

Reactivity

Human

Predicted Reactivity

Application

IF,ICC,ELISA

Application Image

Recommended Dilution

IF 1:50-1:200
ICC 1:100-1:400
ELISA 1:5000-1:20000

Mol Weight

111.110 kDa ;

Gene Symbol

PARG

Uniprot

q86w56

Uniprot link

Immunogen

Recombinant Human Poly(ADP-ribose) glycohydrolase protein (1-348AA)

Immunogen Range

Source

Rabbit

Clonality

Polyclonal

Isotype

IgG

Specificity

Subcellular location

Research Area

Epigenetics and Nuclear Signaling

Positive control

Conjugation

Modification

Purification

>95%, Protein G purified

Formulation

Concentration

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

产品介绍

Clone

Target

波长

Storage

Store at -20°C. Do not aliquot the antibody

注意事项

Companion Products

Important

Comments

RRID

客户评价

艾比玛特医药科技(上海)有限公司
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技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
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华北经销商负责(北京,天津,河北):
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南方经销商负责:

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北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

46c73bc4c7a4d51a3ce472aedb80205b_compress.jpg

      微信客服

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