PK04012

货号 规格 价格(¥)
PK04012S 50μl
PK04012M 100μl

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-CX3CL1 Antibody

Datasheet

Background

Chemokine that acts as a ligand for both CX3CR1 and integrins ITGAV:ITGB3 and ITGA4:ITGB1 . The CX3CR1-CX3CL1 signaling exerts distinct functions in different tissue compartments, such as immune response, inflammation, cell adhesion and chemotaxis . Regulates leukocyte adhesion and migration processes at the endothelium . Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner . In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site (site 1) in integrins . In the absence of CX3CR1, binds to a second site (site 2) in integrins which is distinct from site 1 and enhances the binding of other integrin ligands to site 1 . .; [Processed fractalkine]: The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. .; [Fractalkine]: The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. .; (Microbial infection) Mediates the cytoadherence of erythrocytes infected with parasite P.falciparum (strain 3D7) with endothelial cells by interacting with P.falciparum CBP1 and CBP2 expressed at the surface of erythrocytes . The adhesion prevents the elimination of infected erythrocytes by the spleen (Probable). .

Alternative Name

Fractalkine (C-X3-C motif chemokine 1) (CX3C membrane-anchored chemokine) (Neurotactin) (Small-inducible cytokine D1) [Cleaved into: Processed fractalkine] CX3CL1 FKN NTT SCYD1 A-152E5.2

Reactivity

Mouse;Human

Predicted Reactivity

Application

WB,IHC

Application Image

Recommended Dilution

WB 1:100-1:1000
IHC 1:50-1:200

Mol Weight

42.203kD;

Gene Symbol

CX3CL1 FKN NTT SCYD1 A-152E5.2

Uniprot

p78423

Uniprot link

Immunogen

RKRA04039-Recombinant Chemokine C-X3-C-Motif Ligand 1 (CX3CL1) Gln25~Pro332

Immunogen Range

Source

Rabbit

Clonality

Polyclonal

Isotype

Rabbit IgG

Specificity

Subcellular location

Research Area

Cytokine;Infection immunity;Rheumatology;Autoimmunity;

Positive control

Conjugation

Modification

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Formulation

Liquid

Concentration

500μg/mL

Buffer

0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

产品介绍

Clone

Target

波长

Storage

Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.

注意事项

Companion Products

Important

Comments

RRID

客户评价

艾比玛特医药科技(上海)有限公司
上海市徐汇区桂平路333号聚科生物园区1号楼1-3层

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技术支持:15618194176(微信同号)

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南方经销商负责:

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北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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