Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates . It can phosphorylate a large number of proteins . Participates in Wnt signaling . Phosphorylates CTNNB1 at 'Ser-45' . May phosphorylate PER1 and PER2 (By similarity). May play a role in segregating chromosomes during mitosis . May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration . Acts as a positive regulator of mTORC1 and mTORC2 signaling in response to nutrients by mediating phosphorylation of DEPTOR inhibitor . Acts as an inhibitor of NLRP3 inflammasome assembly by mediating phosphorylation of NLRP3 (By similarity). .
Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1) CSNK1A1
Mouse;Rat;Human
WB,IHC
WB 1:300-1:3000IHC 1:50-1:200
38.915kD;
CSNK1A1
p48729
RKRA66140-Recombinant Casein Kinase 1 Alpha 1 (CSNK1a1) Lys130~Phe337
Rabbit
Polyclonal
Rabbit IgG
Enzyme Kinase;
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Liquid
500μg/mL
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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