Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Sequence-specific DNA-binding transcription factor . Plays a role in hindbrain segmentation by regulating the expression of a subset of homeobox containing genes and in Schwann cell myelination by regulating the expression of genes involved in the formation and maintenance of myelin . Binds to two EGR2-consensus sites EGR2A (5'-CTGTAGGAG-3') and EGR2B (5'-ATGTAGGTG-3') in the HOXB3 enhancer and promotes HOXB3 transcriptional activation . Binds to specific DNA sites located in the promoter region of HOXA4, HOXB2 and ERBB2 . Regulates hindbrain segmentation by controlling the expression of Hox genes, such as HOXA4, HOXB3 and HOXB2, and thereby specifying odd and even rhombomeres . Promotes the expression of HOXB3 in the rhombomere r5 and of HOXB3 in r3 and r5 in the hindbrain . Regulates myelination in the peripheral nervous system after birth, possibly by regulating the expression of myelin proteins, such as MPZ, and by promoting the differentiation of Schwann cells . Involved in the development of the jaw openener musculature, probably by playing a role in its innervation through trigeminal motor neurons . May play a role in adipogenesis, possibly by regulating the expression of CEBPB . .; E3 SUMO-protein ligase helping SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 transcriptional activity. .
E3 SUMO-protein ligase EGR2 (EC 2.3.2.-) (E3 SUMO-protein transferase ERG2) (Early growth response protein 2) (EGR-2) (Zinc finger protein Krox-20) Egr2 Egr-2 Krox-20 Zfp-25
Mouse
WB,IHC
WB 1:300-1:1000IHC 1:50-1:200
49.819kD;
Egr2 Egr-2 Krox-20 Zfp-25
p08152
RKRB45148-Recombinant Early Growth Response Protein 2 (EGR2) Gly150~Ser407 (Accession # P08152)
Rabbit
Polyclonal
Rabbit IgG
Nucleus localization
Tumor immunity;Infection immunity;Neuro science;
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Liquid
500μg/mL
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
艾比玛特医药科技(上海)有限公司
上海市徐汇区桂平路333号聚科生物园区1号楼1-3层
邮箱:market@ab-mart.com
应聘职位:hr@ab-mart.com
订购专线:4006-123-828
销售电话:13916964679(微信同号)
技术支持:15618194176(微信同号)
华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:
陆经理:手机13122837132(微信同号)
北方及西南经销商负责:
张经理:手机13122150513(微信同号)

微信客服
邮箱:market@ab-mart.com
应聘职位:hr@ab-mart.com
订购专线:4006-123-828
销售电话:13916964679(微信同号)
技术支持:15618194176(微信同号)
华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:
陆经理:手机13122837132(微信同号)
北方及西南经销商负责:
张经理:手机13122150513(微信同号)

微信客服
沪ICP备17056956号-2 艾比玛特医药科技(上海)有限公司