13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Plays a role in the cellular breakdown of insulin, APP peptides, IAPP peptides, natriuretic peptides, glucagon, bradykinin, kallidin, and other peptides, and thereby plays a role in intercellular peptide signaling . Substrate binding induces important conformation changes, making it possible to bind and degrade larger substrates, such as insulin . Contributes to the regulation of peptide hormone signaling cascades and regulation of blood glucose homeostasis via its role in the degradation of insulin, glucagon and IAPP (By similarity). Plays a role in the degradation and clearance of APP-derived amyloidogenic peptides that are secreted by neurons and microglia (Probable) . Degrades the natriuretic peptides ANP, BNP and CNP, inactivating their ability to raise intracellular cGMP . Also degrades an aberrant frameshifted 40-residue form of NPPA (fsNPPA) which is associated with familial atrial fibrillation in heterozygous patients . Involved in antigen processing. Produces both the N terminus and the C terminus of MAGEA3-derived antigenic peptide (EVDPIGHLY) that is presented to cytotoxic T lymphocytes by MHC class I. .; (Microbial infection) The membrane-associated isoform acts as an entry receptor for varicella-zoster virus (VZV). .
Insulin-degrading enzyme (EC 3.4.24.56) (Abeta-degrading protease) (Insulin protease) (Insulinase) (Insulysin) IDE
Mouse;Human
WB,IHC,IF,ICC
WB 1:300-1:1000IHC 1:50-1:200IF 1:100-1:400ICC 1:100-1:400
117.968kD;
IDE
p14735
RKRB89734-Recombinant Insulin Degrading Enzyme (IDE) Ala753~Pro973
Rabbit
Polyclonal
Rabbit IgG
Enzyme Kinase;Metabolic pathway;Endocrinology;Cardiovascular biology;
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Liquid
500μg/mL
0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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