PK20765

货号 规格 价格(¥)
PK20765S 50μl
PK20765M 100μl

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-MBD2 Antibody

Datasheet

Background

Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides . Binds hemimethylated DNA as well . Recruits histone deacetylases and DNA methyltransferases to chromatin . Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin . Acts as a transcriptional repressor and plays a role in gene silencing . Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression . May enhance the activation of some unmethylated cAMP-responsive promoters . .

Alternative Name

Methyl-CpG-binding domain protein 2 (Demethylase) (DMTase) (Methyl-CpG-binding protein MBD2) MBD2

Reactivity

Mouse;Rat;Human

Predicted Reactivity

Application

WB,IHC

Application Image

Recommended Dilution

WB 1:300-1:1000
IHC 1:50-1:200

Mol Weight

43.255kD;

Gene Symbol

MBD2

Uniprot

q9ubb5

Uniprot link

Immunogen

RKRC20713-Recombinant Methyl CpG Binding Domain Protein 2 (MBD2) Glu145~Ala411

Immunogen Range

Source

Rabbit

Clonality

Polyclonal

Isotype

Rabbit IgG

Specificity

Subcellular location

Nucleus localization

Research Area

Signal transduction;

Positive control

Conjugation

Modification

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Formulation

Liquid

Concentration

0.5mg/ml

Buffer

0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

产品介绍

Clone

Target

波长

Storage

Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.

注意事项

Companion Products

Important

Comments

RRID

客户评价

艾比玛特医药科技(上海)有限公司
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华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

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北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

46c73bc4c7a4d51a3ce472aedb80205b_compress.jpg

      微信客服

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