M24002

货号 规格 价格(¥)
M24002S 50ul
M24002M 100μl

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-Beta-Catenin (44C6) mAb

Datasheet

Background

The catenins, α, and y, are proteins which bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. α-catenin was initially described as an E-cadherin
associated protein, and since has been shown to associate with other members of the cadherin family, such as N- cadherin and P-cadherin. -catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. -catenin has also been found in complexes with the tumor suppressor protein APC. y-catenin, also known as plakoglobin, is a protein that binds with α-catenin and N-cadherin. It has been shown that the
transmembrane phosphatase PTPμ associates with catenin/cadherin complexes and may regulate complex signaling.

Alternative Name

Catenin beta-1 (Beta-catenin) CTNNB1 CTNNB OK/SW-cl.35 PRO2286

Reactivity

Human, Mouse, Rat

Predicted Reactivity

Application

WB,IHC,IF,ICC,IP

Application Image

Recommended Dilution

WB 1:1000
IHC 1:200
IF 1:200
ICC 1:100-1:400
IP 1:50

Mol Weight

92kDa

Gene Symbol

CTNNB1 CTNNB OK/SW-cl.35 PRO2286

Uniprot

p35222

Uniprot link

Immunogen

This Abmart monoclonal antibody is produced by immunizing mice with a synthetic peptide (KLH-coupled) corresponding to carboxy-terminal residues of human -catenin.

Immunogen Range

Source

Mouse

Clonality

Monoclonal

Isotype

Mouse IgG1

Specificity

-Catenin (44C6) Mouse mAb detects endogenous levels of total -catenin protein.

Subcellular location

Research Area

Cell adhesion

Positive control

Conjugation

Modification

Purification

Formulation

Concentration

Buffer

PBS, pH 7.4, 40% glycerol, and 0.01% sodium azide.

产品介绍

Clone

Target

波长

Storage

Store at -20°C, stable for one year from the date of shipment.

注意事项

Companion Products

#M21001 Goat Anti-Mouse IgG-HRP

Important

Comments

RRID

AB_2920853

客户评价

艾比玛特医药科技(上海)有限公司
上海市徐汇区桂平路333号聚科生物园区1号楼1-3层

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应聘职位:hr@ab-mart.com

订购专线:4006-123-828

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技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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