Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. An allelic polymorphism in this gene results in both functional and non-functional alleles; the reference genome represents the functional allele. Two transcript variants encoding the same protein have been found for this gene.
C-C chemokine receptor type 5 (C-C CKR-5) (CC-CKR-5) (CCR-5) (CCR5) (CHEMR13) (HIV-1 fusion coreceptor) (CD antigen CD195) CCR5 CMKBR5
Human,Rat
WB,IHC,FC
WB 1:500-1:2000IHC 1:50-1:200FC 1:100-1:200
40.5kDa
CCR5 CMKBR5
swissprot: p51681 human
Mouse
Monoclonal
Mouse IgG1
Transmembrane
Immunology->Innate Immunity->Macrophage / Inflamm;Immunology->Immune System Diseases->Antiviral Signaling->HIV-related;Immunology->Innate Immunity->Chemokines->Beta Chemokine Rec. (CCR);Neuroscience->Neurology process->Neurogenesis;Neuroscience->Neurology process->Neurodegenerative disease->Alzheimer's disease->Other;Microbiology->Interspecies Interaction->Host Virus Interaction;Cancer->Signal transduction->G protein signaling->GPCR
MOLT4, L-02, SPA-C-1, A549, and C6 cell lysate, K562 cells, cervical cancer tissues, bladder cancer tissues
Protein G affinity purified.
Liquid
1 mg/mL
1*PBS with 0.05% sodium azide.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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订购专线:4006-123-828
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华南经销商负责(广东,广西,福建,海南):
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