MU115307

货号 规格 价格(¥)
MU115307S 50μl
MU115307M 100μl

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

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经典一抗-CD11b/ITAM antibody

Datasheet

Background

Integrin M, also designated complement component receptor-3 , CD11b (p170), macrophage antigen a polypeptide, cell surface glycoprotein Mac-1 a subunit, MAC1A, MO1A and ITGAM) is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin M combines with the Integrin ∫2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin M/∫2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.

Alternative Name

Integrin alpha-M (CD11 antigen-like family member B) (CR-3 alpha chain) (Cell surface glycoprotein MAC-1 subunit alpha) (Leukocyte adhesion receptor MO1) (Neutrophil adherence receptor) (CD antigen CD11b) ITGAM CD11B CR3A

Reactivity

Human,Mouse

Predicted Reactivity

Application

WB,IF,ICC,IP,FC

Application Image

Recommended Dilution

WB 1:500
IF 1:50-500
ICC 1:100-1:400
IP 1-2 μg per 100-500 μg of total protein1:ml of cell lysate
FC 1μg per 1*10^6 cells

Mol Weight

170kDa

Gene Symbol

ITGAM CD11B CR3A

Uniprot

swissprot: p11215 human

Uniprot link

Immunogen

Immunogen Range

Source

Mouse

Clonality

Monoclonal

Isotype

Mouse IgG1

Specificity

Subcellular location

Transmembrane

Research Area

Stem cells->Mesenchymal Stem Cells->Negative Markers;Stem cells->Hematopoietic Progenitors->Lymphoid->T Lymphocytic Lineage;Stem cells->Hematopoietic Progenitors->Lymphoid->B Lymphocytic Lineage;Stem cells->Hematopoietic Progenitors->Lymphoid->NK Cell Lineage;Stem cells->Hematopoietic Progenitors->Hematopoietic Stem Cells->Murine Lineage Negative

Positive control

PBL, RAW 264.7.

Conjugation

Modification

Purification

Protein A affinity purified.

Formulation

Liquid

Concentration

2 mg/mL.

Buffer

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

产品介绍

Clone

Target

波长

Storage

Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.

注意事项

Companion Products

Important

Comments

RRID

客户评价

艾比玛特医药科技(上海)有限公司
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北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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