MU120859

货号 规格 价格(¥)
MU120859S 50μl
MU120859M 100μl

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-COX2 antibody

Datasheet

Background

Prostaglandins are a diverse group of autocrine and paracrine hormones thatmediate many cellular and physiologic processes. Prostaglandin H2 (PGH2) isan intermediate molecule in formation of the prostaglandins. Cyclooxygenase-1(Cox-1) and cyclooxygenase-2 (Cox-2) are prostaglandin synthases that catalyzethe formation of PGH2 from arachidonic acid (AA). Cox-1 and Cox-2 areisozymes of prostaglandin-endoperoxidase synthase (PTGS). Cox-1 is constitutivelyexpressed in most tissues and is thought to serve in general “housekeeping”functions. Cox-2 is efficiently induced in migratory cells respondingto pro-inflammatory stimuli and is considered to be an important mediator ofinflammation. Both enzymes are targets for the nonsteroidal therapeutic antiinflammatorydrugs, NSAIDs.

Alternative Name

Prostaglandin G/H synthase 2 (EC 1.14.99.1) (Cyclooxygenase-2) (COX-2) (PHS II) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (Prostaglandin-endoperoxide synthase 2) PTGS2 COX2

Reactivity

Human,Mouse,Rat

Predicted Reactivity

Application

WB,IHC,IF,ICC,IP,ELISA

Application Image

Recommended Dilution

WB 1:100-1:1000
IHC 1:50-1:500
IF 1:50-1:500
ICC 1:100-1:400
IP 1-2 μg per 100-500 μg of total protein 1:ml of cell lysate
ELISA 1:30-1:3000

Mol Weight

70-72kDa

Gene Symbol

PTGS2 COX2

Uniprot

swissprot: p35354 human

Uniprot link

Immunogen

Immunogen Range

Source

Mouse

Clonality

Monoclonal

Isotype

Mouse IgG

Specificity

Subcellular location

Research Area

Immunology->Innate Immunity->Macrophage / Inflamm;Cancer->Cancer Metabolism->Metabolic signaling pathway->Hormone biosynthesis;Cancer->Tumor biomarkers->Other;Metabolism->Pathways and Processes->Metabolic signaling pathways->Lipid and lipoprotein metabolism->Cholesterol Metabolism;Metabolism->Pathways and Processes->Metabolic signaling pathways->Lipid and lipoprotein metabolism->Lipoprotein metabolism;Metabolism->Pathways and Processes->Endocrine metabolism->Hormone biosynthesis;Metabolism->Types of disease->Cancer

Positive control

RAW 264.7, NIH/3T3, human gall bladder tissue.

Conjugation

Modification

Purification

Immunogen affinity purified.

Formulation

Liquid

Concentration

2 mg/mL.

Buffer

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

产品介绍

Clone

Target

波长

Storage

Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.

注意事项

Companion Products

Important

Comments

RRID

客户评价

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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