Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Members of the LDL receptor gene family, including LDLR (low density lipoprotein receptor), LRPs (low density lipoprotein related proteins), megalin (also designated GP330), VLDLR (very low density lipoprotein receptor) and ApoER2, are characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. LRP1, also designated α-2-macroglobulin receptor, is a endocytic receptor that mediates the uptake of at least 15 ligands, including α-2-macroglobulin and ApoE. LRP1, which is expressed in brain, liver and lung, is also implicated in Alzheimer's disease (AD), as the human LRP1 gene localizes to a potential AD locus on chromosome 12. The human LRP6 gene localizes to chromosome 12p13.2 and encodes a protein with a unique pattern of four epidermal growth factor (EGF) and three LDLR repeats in the extracellular domain. LRP6 mediates Wnt/β-catenin signaling, which controls various developmental processes, including patterning of the body axis, central nervous system and limbs, and regulation of organogenesis.
Low-density lipoprotein receptor-related protein 6 (LRP-6) LRP6
Human,Mouse
WB,IHC,IF,ICC,IP
WB 1:100-1:1000IHC 1:50-1:500IF 1:50-1:500ICC 1:100-1:400IP 1-2 μg per 100-500 μg of total protein1:ml of cell lysate
183 kDa
LRP6
swissprot: o75581 human
Mouse
Monoclonal
Mouse IgG1
Transmembrane
Stem cells->Signaling Pathways->Wnt->Surface Molecules
Hela, human duodenum tissue.
Protein A affinity purified.
Liquid
2 mg/mL.
1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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订购专线:4006-123-828
销售电话:13916964679(微信同号)
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华南经销商负责(广东,广西,福建,海南):
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