13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Interleukin-6, or IL-6, is a multifunctional protein, 212 amino acids in length, that plays critical roles in host defense, immune response and hematopoiesis. IL-6 is constitutively expressed by epidermal Langerhans cells and its expression is induced in stimulated keratinocytes. IL-6, IL-1β and TNFα act as endogenous pyrogens, regulating the fever response to bacterial invasion. The IL-6 receptor is a trimeric complex composed of an IL-6-specific α chain and a homodimer of the gp130 glycoprotein common to the IL-6, IL-11, CNTF, OSM and LIF receptors. Stimulation with IL-6 leads to gp130 homodimerization and the activation of associated kinases JAK1 and JAK2. Once activated, JAK1 and JAK2 phosphorylate Stat3, causing its nuclear translocation and transcription of Stat3-responsive genes. IL-6 has also been shown to activate the Ras/MAP kinase pathway, which regulates NFIL6 transcription.
Interleukin-6 (IL-6) (B-cell stimulatory factor 2) (BSF-2) (CTL differentiation factor) (CDF) (Hybridoma growth factor) (Interferon beta-2) (IFN-beta-2) IL6 IFNB2
Mouse,Rat
WB,IF,ICC
WB 1:500-1:2000
IF 1:100-1:400
ICC 1:50-1:200
24 kDa
IL6 IFNB2
swissprot: p05231 human;swissprot: p08505 mouse;swissprot: p20607 rat
Mouse
Monoclonal
Mouse IgG2b
Immunology-&>Innate Immunity-&>Cytokines-&>Interleukins;Neuroscience-&>Neurology process-&>Metabolism;Cancer-&>Invasion/microenvironment-&>Apoptosis-&>Death receptors ligands-&>TRAF;Cancer-&>Invasion/microenvironment-&>Apoptosis-&>Caspases;Cancer-&>Invasion/microenvironment-&>Apoptosis-&>Cytochrome C;Cancer-&>Invasion/microenvironment-&>Apoptosis-&>Chromatin condensation;Cancer-&>Invasion/microenvironment-&>Angiogenesis-&>Angiogenic growth factors;Cancer-&>Invasion/microenvironment-&>Angiogenesis-&>ECM enzymes-&>TIMPs;Cancer-&>Invasion/microenvironment-&>Angiogenesis-&>Angiogenic inhibitory factors;Cancer-&>Invasion/microenvironment-&>Angiogenesis-&>Other;Cancer-&>Invasion/microenvironment-&>Hypoxia-&>Hydroxylases;Cancer-&>Tumor biomarkers-&>Tumor antigens;Cancer-&>Tumor immunology-&>Cytokines-&>Interleukins;Metabolism-&>Types of disease-&>Cancer;Metabolism-&>Types of disease-&>Obesity
Recombinant protein lysates, PC-3M, Hela, NIH/3T3, mouse spleen tissue.
Protein G affinity purified.
Liquid
2 mg/mL.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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