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Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
SATB2 (special AT-rich sequence-binding protein 2) is a nuclear matrix protein that influences craniofacial formation mechanisms, such as jaw and palate development, and is part of a transcriptional network regulating skeletal development and osteoblast differentiation. Highly expressed in adult and fetal brain, SATB2 contains two CUT DNA-binding domains and one homeobox domain and is closely related to SATB1, a transcriptional repressor. SATB2 is thought to bind to matrix attachment regions (MARs) and regulate MAR-dependent transcription of various genes, including HoxA2 and ATF-4 (CREB-2), involved in skeletal development. Functioning as both a transcriptional activator and repressor, SATB2 can also act as a protein scaffold that can enhance the activity of other DNA-binding proteins. Defects in the gene encoding SATB2 are the cause of cleft palate manifested in conjunction with severe mental retardation.
DNA-binding protein SATB2 (Special AT-rich sequence-binding protein 2) SATB2 KIAA1034
Human,Mouse,Rat
WB,IF,ICC,IP
WB 1:100-1:1000IF 1:50-1:500ICC 1:100-1:400IP 1-2 μg per 100-500 μg of total protein1:ml of cell lysate
105kDa
SATB2 KIAA1034
swissprot: q9upw6 human
Mouse
Monoclonal
Mouse IgG1
Nucleus localization
Neuroscience->Neurology process->Neurogenesis
KNRK, HT-1080, SH-SY5Y
Protein A affinity purified.
Liquid
2 mg/mL.
1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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订购专线：4006-123-828
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程经理：手机18616261485（微信同号）
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