Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Products of the highly conserved Wnt gene family, including Wnt-1 through Wnt-10, play key roles in regulating cellular growth and differentiation. Wnt-1 is a cysteine-rich, secreted glycoprotein that associates with cell membranes and likely functions as a key regulator of cellular adhesion. Wnt-1, which is essential for normal development of the embryonic nervous system, contributes to hyperplasia and tumorigenic progression when improperly expressed in mammary tissue. Wnt-3 is also involved in tumorigenesis, and Wnt-2 and Wnt-4 may be associated with abnormal proliferation in human breast tissue.Wnt-1, Wnt-3 and Wnt-10b have been implicated along with FGF-3 in the development of mouse mammary tumor virus-induced mouse mammary carcinomas.Wnt family members have been shown to interact with Sonic hedgehog (Shh) in vivo to induce myogenesis in somitic tissue.
Protein Wnt-4 WNT4 UNQ426/PRO864
Human,Mouse,Rat
WB,IHC,IF,ICC,IP
WB 1:1000IHC 1:50-500IF 1:50-500ICC 1:100-1:400IP 1-2 μg per 100-500 μg of total protein
40 kDa
WNT4 UNQ426/PRO864
swissprot: p56705 human
Mouse
Monoclonal
Mouse IgG1
Stem cells->Signaling Pathways->Wnt->Secreted;Developmental Biology->Reproduction->Placental development;Developmental Biology->Reproduction->Sex determination;Developmental Biology->Organogenesis->Excretory system development->Kidney development
L929, CSMLO, ESD3, ESD5, human spleen tissue.
Protein A affinity purified.
Liquid
2 mg/mL.
1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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