13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
The Yes-associated protein, otherwise known as YAP, is a 14-3-3-bindingmolecule that was originally recognized by virtue of its ability to bind to theSH3 domain of Yes. The binding of YAP to 14-3-3 requires the phosphorylationof a homologous serine residue (Ser 112) in the YAP 14-3-3-binding motif. Thehighly conserved and ubiquitously expressed 14-3-3 proteins regulate differentiation,cell cycle progression and apoptosis by binding intracellular phosphoproteinsinvolved in signal transduction. YAP may link events at the plasmamembrane and cytoskeleton to inhibition of transcription in the nucleus in amanner regulated by 14-3-3 proteins. YAP shares homology with the WWdomain of TAZ, transcriptional co-activator with PDZ-binding motif, whichfunctions as a transcriptional co-activator by binding to the PPXY motif presentin transcription factors. YAP is expressed at high levels in the lung, placenta,prostate, ovary and testis.
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog) YAP1 YAP65
Human,Mouse,Rat
WB,IF,ICC,IP
WB 1:100-1:1000IF 1:50-1:500ICC 1:100-1:400IP 1-2 μg per 100-500 μg of total protein1:ml of cell lysate
65kDa
YAP1 YAP65
swissprot: p46937 human
Mouse
Monoclonal
Mouse IgG1
DNA damage
293T, Caco-2
Protein A affinity purified.
Liquid
2 mg/mL.
1*PBS (pH7.4), 1% Geltin, 0.05% Sodium Azide.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
艾比玛特医药科技（上海）有限公司
上海市徐汇区桂平路333号聚科生物园区1号楼1-3层
邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
沪ICP备17056956号-2 艾比玛特医药科技（上海）有限公司
