Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. ACTC1 encodes cardiac muscle alpha actin. This isoform differs from the alpha actin that is expressed in skeletal muscle, ACTA1. Alpha cardiac actin is the major protein of the thin filament in cardiac sarcomeres, which are responsible for muscle contraction and generation of force to support the pump function of the heart. ACTA2 (actin alpha 2) is an actin protein with several aliases including alpha-actin, alpha-actin-2, aortic smooth muscle or alpha smooth muscle actin (α-SMA, SMactin, alpha-SM-actin, ASMA). Actins are a family of globular multi-functional proteins that form microfilaments. ACTA2 is one of 6 different actin isoforms and is involved in the contractile apparatus of smooth muscle. ACTA2 (as with all the actins) is extremely highly conserved and found in nearly all mammals. Actin, alpha skeletal muscle is a protein that in humans is encoded by the ACTA1 gene. Actin alpha 1 which is expressed in skeletal muscle is one of six different actin isoforms which have been identified. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Alpha actins are a major constituent of the contractile apparatus.

Actin, alpha skeletal muscle (EC 3.6.4.-) (Alpha-actin-1) [Cleaved into: Actin, alpha skeletal muscle, intermediate form] ACTA1 ACTA

Human,Mouse,Rat

WB,IHC

WB 1:500-1:2000
IHC 1:100-1:500

42kDa

ACTA1 ACTA

swissprot: p68133 human;swissprot: p68032 human;swissprot: p62736 human;swissprot: p68134 mouse;swissprot: p68033 mouse;swissprot: p62737 mouse;swissprot: p68136 rat;swissprot: p68035 rat;swissprot: p62738 rat

https://www.uniprot.org/uniprotkb/p68133

Mouse

Monoclonal

Mouse IgG1

Stem cells->Mesenchymal Stem Cells->Myogenesis;Stem cells->Lineage Markers->Mesoderm;Developmental Biology->Lineage specification->Mesoderm;Cancer->Invasion/microenvironment->Apoptosis->Death receptors ligands->RIP;Cancer->Invasion/microenvironment->Apoptosis->Death receptors ligands->TRAF;Cancer->Invasion/microenvironment->Apoptosis->Death receptors ligands->FADD;Cancer->Invasion/microenvironment->Apoptosis->Death receptors ligands->TRADD;Cancer->Invasion/microenvironment->Apoptosis->Caspases;Cancer->Invasion/microenvironment->Apoptosis->Cytochrome C;Cancer->Invasion/microenvironment->Angiogenesis->Angiogenic growth factors;Cancer->Invasion/microenvironment->Angiogenesis->Angiogenic inhibitory factors;Cancer->Invasion/microenvironment->Angiogenesis->Other;Cancer->Invasion/microenvironment->Hypoxia->HIF;Cancer->Invasion/microenvironment->Hypoxia->Hydroxylases;Cancer->Tumor biomarkers->Tumor antigens;Cancer->Tumor biomarkers->Enzymes->Other;Cancer->Cell Death->Apoptosis->Receptors->Death receptors ligands->RIP

Rat heart tissue lysate, mouse smooth muscle tissue lysate, human skeletal muscle tissue lysate.

Protein A affinity purified.

Liquid

2 mg/mL.

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.