13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Pdcd-1 (Programmed Cell Death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. Pdcd-1 contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) within the cytoplasmic domain, which is conserved between the mouse and human homologs. Expression of Pdcd-1 is detected in mouse thymus, and it is induced in stimulated B and T cell lines, where it may play a role in the negative regulation of various immune responses. Receptors such as Pdcd-1 function by recruiting tyrosine phosphatases, including SHP-1 and SHIP, which are responsible for altering various B cell responses. Additionally, in activated lymphocytes, Pdcd-1 mediates the activation of the classical type of programmed cell death.
Programmed cell death protein 1 (Protein PD-1) (hPD-1) (CD antigen CD279) PDCD1 PD1
Human
WB,IHC,IF,ICC,FC
WB 1:500-1:2000IHC 1:100-1:500IF 1:100-1:400ICC 1:50-1:200FC 1:50-1:100
32 kDa
PDCD1 PD1
swissprot: q15116 human
Mouse
Monoclonal
Mouse IgG1
Transmembrane
Immunology->Adaptive Immunity->Regulatory T Cells;Immunology->Adaptive Immunity->T Cells->CD;Cell Biology->Apoptosis->Receptors->Death Receptors;Cancer->Invasion/microenvironment->Apoptosis->Other;Cancer->Invasion/microenvironment->Apoptosis->Death receptors ligands->IAPs;Cancer->Invasion/microenvironment->Apoptosis->Caspases;Cancer->Invasion/microenvironment->Angiogenesis->Other;Cancer->Tumor biomarkers->Tumor antigens;Cancer->Cell Death->Apoptosis->Other;Cancer->Tumor immunology->CD markers
Human tonsil tissue, Mouse spleen tissue, Jurkat, recombinant PD1 protein.
Protein A affinity purified.
Liquid
2 mg/mL.
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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